![]() ![]() ![]() The aim of this study was to analyze the role of PJC for the prediction of malignant IPMN (IPMC). Routine use of PJC is not recommended in the European 10 and American guidelines 11, whereas it is recommended only for research purposes in the ICG 2012 and the 2017 revision of the guidelines 3, 12. ![]() Pancreatic juice cytology (PJC) is an important factor for detecting malignant IPMN 6 and its importance for the differentiation between benign and malignant IPMNs has been reported 7, 8, 9. However, the overestimation of benign lesions with subsequent unnecessary surgery for patients with benign IPMN is still a major concern of using the ICG 2012. ![]() International consensus guidelines (ICG) were formulated in 2006 4, 5 and were refined in 2012 3. These include: the main duct (MD-IPMN), which are characterized by segmental or diffuse dilation of the main pancreatic duct (MPD) of > 5 mm without other causes of obstruction branch duct (BD-IPMN), defined as pancreatic cysts of > 5mm in diameter that communicate with the MPD and a mixed type. IPMN are classified according to the involvement of pancreatic ducts. Compared to noninvasive IPMN, invasive cancers have a distinct poorer prognosis, with a five-year overall survival rate of 36-70% 1, 2 ). Pancreatic intraductal papillary mucinous neoplasm (IPMN) has a variable malignant potential that ranges from premalignant intraductal lesions to malignant neoplasms with invasive carcinoma. ![]()
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